What Is Methylsulfonylmethane?
Methylsulfonylmethane (MSM) is an organosulfur compound, characterized by a sulfone group bonded to two methyl groups. It presents as a white solid at room temperature, with a melting point of 108-111°C and a boiling point of 238°C. MSM is soluble in water, acetone, and ethanol, found naturally in various foods, human cartilage, muscles, skin, hair, and nails, and is noted for its analgesic and anti-inflammatory properties.
Uses of Methylsulfonylmethane
Methylsulfonylmethane is recognized for its role in protein, collagen, and keratin production, contributing to healthy collagen levels and alleviating pain and inflammation, such as joint and back pain. Its benefits, particularly in humans, remain under-researched, although its potential effects on arthritis have been explored in animal studies. MSM is also incorporated into cosmetics, lotions, and dietary supplements.
Properties of Methylsulfonylmethane
As a colorless liquid at room temperature, Methylsulfonylmethane is hygroscopic and demonstrates high polarity, making it soluble in water and organic solvents like methanol. Chemically stable, it resists decomposition at elevated temperatures and, despite containing sulfur, is odorless and has a bitter taste.
Structure of Methylsulfonylmethane
The molecular structure of methylsulfonylmethane includes two methyl groups attached to a sulfonyl group, lending the compound its polar nature. This polarity influences its intermolecular interactions and solubility.
Other Information on Methylsulfonylmethane
1. Effects of Methylsulfonylmethane
Arthritis: Methylsulfonylmethane may inhibit joint tissue degradation and relieve rheumatic pain. A study involving knee osteoarthritis patients reported improved pain scores with a 12-week course of MSM.
Seasonal Allergic Rhinitis: Research indicates MSM’s effectiveness in mitigating allergic rhinitis symptoms, without affecting histamine or IgE levels.
Interstitial Cystitis: Methylsulfonylmethane has been reported to alleviate symptoms of interstitial cystitis, a condition more prevalent among women in the U.S.
2. Production of Methylsulfonylmethane
Methylsulfonylmethane is produced by oxidizing dimethyl sulfoxide (DMSO) with hydrogen peroxide. Post-reaction, MSM is isolated through distillation and then spray-dried to form a crystalline powder.
3. Safety Information on Methylsulfonylmethane
Generally considered safe, MSM’s side effects are minimal when used appropriately. However, its safety for pregnant women, nursing mothers, and topical applications requires further information. Caution is advised regarding the intake levels specified on U.S. imports.