What Is Arsenic Trioxide?
Arsenic trioxide, with the chemical formula As2O3, is an oxide of arsenic known also by its CAS number 1327-53-3. It occurs naturally in minerals such as arsenopyrite and cladoclase but is highly toxic, evidenced by historical incidents like the Dorokyu Mine tragedy.
Uses of Arsenic Trioxide
Despite its toxicity, arsenic trioxide has been used as a rat poison, insecticide, pesticide, and in medicine for treating tooth decay and leukemia. Its industrial applications include manufacturing metallic arsenic, arsenic compounds, glass decolorization, dye production, and semiconductor doping.
Properties of Arsenic Trioxide
Arsenic trioxide is a colorless, odorless solid with a melting point of 312.2°C and a boiling point of 465°C. It sublimates into a toxic gas when heated and dissolves in water to form slightly acidic arsenite, showcasing unique chemical and physical properties.
Types of Arsenic Trioxide
Primarily available for research and development, arsenic trioxide is sold in various quantities suitable for laboratory use. It must be handled according to strict safety protocols due to its toxic nature.
Other Information on Arsenic Trioxide
1. Synthesis of Arsenic Trioxide
Produced by oxidizing arsenic sulfide or hydrolyzing arsenic trichloride, arsenic trioxide’s synthesis highlights its reactive nature.
2. Chemical Reaction of Arsenic Trioxide
As an amphoteric oxide, it reacts with both acids and bases, and strong oxidizers convert it to arsenic acid or arsenic pentaoxide, indicating its chemical versatility.
3. Toxicity of Arsenic Trioxide
Its classification under various GHS categories emphasizes the significant health risks associated with arsenic trioxide, including its potential for causing acute toxicity, eye irritation, genetic disorders, carcinogenicity, and reproductive toxicity.
4. Regulatory Information on Arsenic Trioxide
Regulated under numerous health and safety laws, arsenic trioxide’s management is subject to strict compliance requirements, reflecting its hazardous status.