What Is Distigmine?
Distigmine, also known as distigmine bromide, is a chemical compound with the formula C22H32Br2N4O4.
Distigmine functions by inhibiting cholinesterase, an enzyme that breaks down acetylcholine—a key neurotransmitter in parasympathetic and motor nerves. By inhibiting cholinesterase, distigmine helps maintain higher levels of acetylcholine.
Uses of Distigmine
Distigmine is utilized in medical treatments due to its cholinesterase-inhibitory properties.
It plays a crucial role in enhancing muscle contraction, particularly beneficial in conditions like hypotonic bladder.
Additionally, distigmine is effective in treating myasthenia gravis, an autoimmune disorder that weakens muscles. It increases acetylcholine levels, thereby improving nerve-muscle signal transmission.