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Myrcene

What Is Myrcene?

Basic information about Myrcene

Figure 1. Basic Information on Myrcene

Myrcene, a naturally occurring organic compound with the formula C10H16, is notable for its presence in laurel, pine, wormwood, and mints. As β-myrcene, it serves as a pheromone for woodlice and an attractant, while being handled carefully due to its classification under fire laws.

Uses of Myrcenes

Valued for its muscle relaxant, sedative, anti-inflammatory, and antibacterial properties, myrcene is utilized in dietary supplements, aroma oils, and the fragrance industry. It’s a precursor for various fragrances like menthol and citral and is involved in resin production.

Properties of Myrcenes

Myrcene exhibits a fresh coniferous aroma, with a melting point of 50°C and a boiling point of 166-168°C. It tends to polymerize at room temperature, enhancing its chemical interest.

Structure of Myrcenes

Structure of Myrcene

Figure 2. Myrcene Structure

As a monoterpene, myrcene consists of two isoprene units, with α-myrcene and β-myrcene as isomers. β-myrcene, predominant in nature, differs from α-myrcene by the position of its double bond.

Other Information on Myrcenes

1. Synthesis of Myrcenes

Synthesis of myrcene

Figure 3. Synthesis of Myrcenes

Commercially, myrcene is mainly produced from the pyrolysis of β-pinene from turpentine oil, with a biosynthesis route involving geranyl diphosphate in plants.

2. Myrcene Reaction

Myrcene is convertible to myrcenol through hydroamination, followed by hydrolysis and amine removal via a palladium catalyst. It participates in Diels-Alder reactions, producing derivatives like hydroxymethylpentylcyclohexenecarboxaldehyde, known as Lyral.

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