What Is L-Canaline?
L-canaline is an alpha-amino acid that does not constitute natural proteins. Its chemical formula is NH2-O-CH2CH2-CH(NH2)-COOH, and it is also known as O-amino-L-homoserine and 2-amino-4-(aminooxy)butyric acid.
This amino acid is produced from canavanine, found in legumes such as nattamame and other beans, through the action of enzymes like arginase or canavanase. L-canaline is structurally similar to ornithine, an alpha-amino acid, and is recognized for its potent insecticidal properties. This effectiveness as an insecticide is attributed to its interaction with keto acids and aldehydes in the body, particularly pyridoxal phosphate, a cofactor essential for various enzymatic reactions.
Uses of L-Canaline
L-canaline’s primary application is as a potent insecticide. It exerts its effect by binding to keto acids and aldehydes in the body, especially pyridoxal phosphate, thereby inhibiting important biological processes such as aminotransferases, and some decarboxylation and deamination reactions. These disruptions make it effective against certain insects.
Aside from its use in pest control, L-canaline has limited industrial applications. It is occasionally utilized in amino acid-based cosmetic products, such as shampoos and hair treatments, due to its properties beneficial for hair repair and maintenance.