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Semicarbazide

What Is Semicarbazide?

Semicarbazide, a urea derivative with the molecular formula CH5N3O, is a versatile organic compound used in various applications, from thin-layer chromatography to organic synthesis, including the production of nitrofuran antimicrobials.

Uses of Semicarbazide

1. General Applications

As a chromogenic reagent and paint hardener, semicarbazide aids in identifying aldehydes and ketones through the formation of semicarbazones, leveraging its reaction with carbonyl compounds to form highly crystalline imine derivatives.

2. Synthetic Applications

It serves as an intermediate in synthesizing antimicrobial agents, highlighting its significance in pharmaceuticals.

Properties of Semicarbazide

A colorless crystalline solid, semicarbazide is soluble in water and ethanol, showcasing a melting point of 96°C and a molecular weight of 75.07.

Types of Semicarbazide

Available primarily as a reagent or industrial chemical in hydrochloride salt form, semicarbazide caters to diverse needs from research to large-scale industrial applications.

Other Information on Semicarbazide

1. Synthesis of Semicarbazide

Semicarbazide is synthesized through reactions involving urea and hydrazine, among other methods, underlining its chemical versatility.

2. Chemical Reaction of Semicarbazide

Its ability to form semicarbazone through condensation with carbonyl compounds is a key feature, aiding in the identification of various substances.

3. Semicarbazide Hydrochloride

Commonly utilized in its hydrochloride form for organic synthesis, semicarbazide hydrochloride embodies the compound’s adaptability in chemical processes.

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