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Isoamyl Acetate

What Is Isoamyl Acetate?

Isoamyl acetate, officially known as isopentyl{[2-(diethylamino)ethyl]amino}(phenyl)acetate and commonly called camylofin, has various aliases including acamylophenin, adpon, avocan, syntespasmil, spasmocan, nabadil, novospasmin, and belosin. It is a pale yellow, oily substance at room temperature with a melting point of 77°F and a boiling range of 330°F to 355°F.

Isoamyl acetate is toxic and can cause acute toxicity if ingested. It poses a danger due to the toxic NOx gases produced by its thermal decomposition and should be handled with care.

Uses of Isoamyl Acetate

As an antispasmodic and antimuscarinic drug, isoamyl acetates are used to treat a variety of conditions. Similar muscarinic choline receptor antagonists include atropine, hyoscitamine, scopolamine, and pilesepine. These drugs are commonly used in the treatment of respiratory disorders like overactive bladder, bradycardia, and asthma, as well as neurological disorders such as Parkinson’s disease and Alzheimer’s disease.

Additionally, isoamyl acetate is effective in treating abdominal pain, particularly in infants and children, and is often combined with acetaminophen to address fever and abdominal pain.

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