What Is Cycloheptane?
Cycloheptane is a cycloalkane (alicyclic organic compound) with the chemical formula C7H14.
It has a seven-membered ring structure. It is also known as heptamethylene, and its CAS number is 291-64-5. It has a molecular weight of 98.2, a melting point of -12°C, and a boiling point of 118°C. It is a colorless, oily liquid at room temperature.
The odor is described as mildly aromatic. It has a density of 0.8110 g/cm3 and is often used as a non-polar solvent. It is readily soluble in ethanol and diethyl ether, and soluble in benzene and chloroform. It is insoluble in water.
Uses of Cycloheptane
Cycloheptane is mainly used as a laboratory chemical for organic chemical analysis and as a raw material for organic synthesis. Due to its structural characteristics as a seven-membered cycloalkane without functional group substitutions, it is used as a nonpolar solvent or as a building block.
In the chemical industry, it is used as a nonpolar solvent and as a synthetic intermediate in the manufacture of chemicals and pharmaceuticals.
Characteristics of Cycloheptane
Cycloheptane is a seven-membered ring, but it does not have a planar structure, so it has a three-dimensional structure with several conformations. There are two stable conformations: twisted chair and twisted boat, with the twisted chair being the most stable.
The other conformations are chair, boat, and T3, which take on these structures in the transition state between stable conformations. The ring contraction reaction under the action of aluminum chloride leads to isomerization and the formation of methylcyclohexane.
It has a low flash point of 6°C and is highly flammable. Exposure to heat or flame poses a high risk of fire. It is highly reactive with oxygen-rich substances, such as strong oxidizers, and must be avoided in storage.
Types of Cycloheptane
Cycloheptane is generally sold as a reagent product for research and development. It is available in 1g, 5g, 25g, 25mL, etc., and is supplied in small and compact volumes that are easy to handle in the laboratory. It is handled as a reagent product that can be stored and transported at room temperature.
Cycloheptane is highly flammable, combustible, and toxic to the human body.
Other Information on Cycloheptane
1. Synthesis of Cycloheptane
Methods for synthesizing cycloheptane include the reduction of the carbonyl group by clemencene reduction of cycloheptanone and cyclization using 1,6-dibromohexane and malonic acid diesters.
2. Safety Information on Cycloheptane
Cycloheptane is highly flammable, combustible, and highly hazardous. It is also toxic to the human body, causing drowsiness and dizziness. The vapors can cause eye irritation, and inhalation of large quantities may cause reduced ventilation.
When handling, it is important to keep the material away from ignition sources, such as heat, sparks, open flames, and hot objects, and to provide ventilation when in use. It is also necessary to use appropriate protective equipment, avoid inhalation of mists, vapors, and sprays, and avoid direct contact.
If contact with the human body occurs, the liquid should be removed promptly by removing clothing or running water. If inhaled, medical attention is required. In addition, when disposing of the product, it is required to outsource the work to a specialized waste disposal company licensed by the prefectural governor and dispose of the product appropriately.